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肠球菌对人类健康:朋友还是敌人?
Yue Wang1, Wenfeng Xu1, Sirui Guo1
1Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk and Individual Application (Beijing Hospital), Beijing, 100730, PR China.
Microbial pathogenesis
|February 21, 2025
概括
肠球菌具有双重性质,在食品保存和作为益生菌方面具有好处,但由于病原性和抗生素耐药性,也存在风险. 本综述分析了它们相互矛盾的作用,以指导安全有效的使用.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 临床医学 临床医学
背景情况:
- 肠球菌是无处不在的微生物,具有工业发酵能力.
- 它们产生细菌素来保存食物,并作为益生菌起作用.
- 然而,因多药性耐药性,Enterococci,特别是Enterococcus faecalis和Enterococcus faecium越来越多地被认为是临床环境中的重要病原体.
研究的目的:
- 综合分析菌的有益和有害特性.
- 为了解决Enterococci的致病性和有益作用的矛盾性质.
- 探索Enterococci在医疗治疗中的潜在用途,并建立安全评估标准.
主要方法:
- 综述了最近Enterococci研究的进展.
- 纳入国际权威组织的观点.
- 分析Enterococci的科学,临床和工业应用.
主要成果:
- 肠球菌表现出有益的特性 (细菌素的产生,益生菌的潜力) 和有害的特性 (致病性,多药物耐药性).
- 特定的物种,如Enterococcus faecalis和Enterococcus faecium与临床疾病有关.
- 需要平衡它们的有益应用与它们所带来的风险.
结论:
- 肠球菌呈现出复杂的形状,需要仔细考虑它们的使用.
- 需要标准化指导方针,以便安全有效地选择和使用菌,特别是作为益生菌.
- 进一步的研究是必不可少的,以利用它们的好处,同时减轻医疗和工业应用中的风险.
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