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Flow Cytometric Isolation of Primary Murine Type II Alveolar Epithelial Cells for Functional and Molecular Studies
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流感病毒诱导的I型干扰素会破坏发育中的肺部中膜上皮的修复和紧密结合的完整性

Abigail P Onufer1, Joshua Chang Mell1, Laura Cort1

  • 1Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.

Mucosal immunology
|February 21, 2025
PubMed
概括

干扰素I (IFN-I) 信号破坏了感染甲型流感病毒 (IAV) 的发育小鼠的肺部修复. 阻断IFN-I改善了新生儿的生存率和肺障碍完整性,与成人反应相反.

关键词:
屏障的完整性 屏障的完整性发展发展发展 发展发展皮质细胞是上皮细胞.流感是一次流感.肺部的修复 肺部的修复儿科 儿科 儿科

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