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Updated: May 26, 2025

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains
09:27

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Published on: January 5, 2016

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重新审视了prolyl oligopeptidase和α-synuclein连接的研究结果

Roos Van Elzen1, Yannick Waumans1, Sangeeta Nath2

  • 1Laboratory of Medical Biochemistry, University of Antwerp, Universiteitsplein 1, B-2610, Wilrijk, Belgium.

Biochimie
|February 21, 2025
PubMed
概括

普罗利寡酶 (PREP) 与α-synuclein (aSyn) 相互作用较弱,促进早期聚合,但不影响纤维细胞的形成. 这种由抑制剂调节的相互作用表明神经元通路中的作用.

关键词:
自自是一种自的过程.这是一种PREP抑制剂.普罗利尔寡酸酶 (prolyl oligopeptidase) 是一种酸.蛋白质分泌 蛋白质分泌贩卖囊泡,贩卖囊泡的行为α-synuclein 是一种同核蛋白.

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Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation09:16

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