三维右心室射出小部分与心脏手术患者的住院结果之间的关联:一个多中心研究
Edith L Posada-Martinez1, Juan B Ivey-Miranda2, Xochitl A Ortiz-Leon1
1Echocardiography Department, Instituto Nacional de Cardiología "Ignacio Chavez", Mexico City, Mexico.
概括
三维右心室喷射分数 (3D RVEF) 是心脏手术患者结果的强有力的预测指标. 纳入3D RVEF可能会改善手术后的风险分层和患者结果.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 准确的风险分层对于心脏手术至关重要.
- 目前的风险评分往往缺乏对右心室 (RV) 功能的评估.
- RV功能障碍会对手术结果产生重大影响.
研究的目的:
- 评估三维RV射出分数 (3D RVEF) 是否可以预测心脏手术患者的结果.
- 将 3D RVEF 的预测值与其他 RV 函数参数进行比较.
- 为了确定3D RVEF是否能改善风险分层,超出了像EuroSCORE II这样的现有分数.
主要方法:
- 未来的多中心研究涉及248名接受心脏手术的成年患者.
- 经食道回声心脏图被用于在手术前分析RV功能参数.
- 评估了3D RVEF与复合初级结果 (住院死亡率或需要心室辅助装置) 的相关性,并对EuroSCORE II进行了调整.
主要成果:
- 在调整为EuroSCORE II (HR=2.46,P=0.028) 后,降低3D RVEF与不良结果独立相关.
- 与其他RV功能参数 (P=0.006) 相比,3D RVEF显示了对主要结果的优异预测能力.
- 患有RVEF降低的患者在30天内显著降低了免于主要终点的存活率 (72%对93%,P<0.001),以及在机械通风和内的更长时间.
结论:
- 三维RV喷射分数是心脏手术患者住院死亡率或需要临时心室辅助装置的最强预测指标.
- 这项研究表明,3D RVEF应纳入心脏外科手术的手术前评估.
- 包括3D RVEF可能会提高心脏手术患者风险分层的准确性.
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