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Updated: May 26, 2025

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在RICTOR中,一种功能增益变异使人产生肥胖的倾向

Mengshan Ni1, Yinmeng Zhu1, Yufei Chen1

  • 1Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai National Center for Translational Medicine, Shanghai 200025, China.

Journal of genetics and genomics = Yi chuan xue bao
|February 21, 2025
PubMed
概括

在RICTOR (RICTOR p.I116V) 中的一种罕见的基因突变与严重肥胖有关. 这种功能增益变体增强了AKT信号传递和脂肪生成,有助于体重增加.

关键词:
在 AKT AKT 里面.增脂生殖是一种增脂的过程.功能获取 - 功能获取肥胖问题 肥胖问题里克托尔是什么意思在 mTORC2 中,mTORC2 是

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