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Updated: May 26, 2025

Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II
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Chromatin Spread Preparations for the Analysis of Mouse Oocyte Progression from Prophase to Metaphase II

Published on: February 26, 2018

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在中间体处的动态R环确保了小鼠在卵细胞中介性分裂期间的染色体对齐

Yinghong Chen1, Liying Wang2, Qiuxing Zhou3

  • 1Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Science bulletin
|February 21, 2025
PubMed
概括

R-循环和RNase H1对于卵细胞半细胞分裂中的染色体对齐至关重要. 它们的失调会导致不育,但ATR,CHK1和Aurora B抑制剂可以挽救这些缺陷.

关键词:
中介质是中介质的组成部分.卵细胞中介性分裂在R-Loop中使用.在RNase H1中.

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