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在台湾评估认知障碍的Cogstate简报电池性能:一个前性的多中心研究

Yi-Chun Kuan¹, Kai-Ming Jhang², Wen-Fu Wang²

¹Department of Neurology, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, 235041, Taiwan; Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan; Taipei Neuroscience Institute, Taipei Medical University, Taipei, 110301, Taiwan; Dementia Center, Shuang-Ho Hospital, Taipei Medical University, New Taipei City, 235041, Taiwan; Department of Biomedical Engineering, National Taiwan University, Taipei, 100233, Taiwan.

Journal of the Formosan Medical Association = Taiwan yi zhi

|February 21, 2025

概括

在Cogstate简要电池 (CBB) 有效选轻度认知障碍和痴呆症在普通话说者. 这种工具有助于早期诊断,并改善了台湾的痴呆症护理途径.

科学领域:

神经学神经学
老年学是一门学科.
认知科学认知科学

背景情况:

早期发现痴呆症对于干预至关重要,但传统评估面临延迟.
康斯泰特简要电池 (CBB) 是一种快速查工具,在普通话人口中有效性有限.
人口老龄化增加了对高效认知评估工具的需求.

研究的目的:

在台湾验证Cogstate简要电池 (CBB) 以区分轻度认知障碍 (MCI) 和痴呆症与健康对照 (HC).
评估CBB在普通话人口中的表现.
评估CBB子分数和大脑年龄对于认知障碍检测的有用性.

主要方法:

一项前性多中心研究,涉及台湾192名参与者.
使用CBB进行认知评估,包括学习/工作记忆大脑性能指数 (Lrn/WM BPI),注意力/精神运动大脑性能指数 (Attn/精神运动 BPI),联合BPI和大脑年龄.
在区分MCI,痴呆症和HC组之间CBB性能的比较.

主要成果:

CBB在认知群体之间表现出强大的歧视力.
综合的BPI实现了区分痴呆症和HC的最高AUC (0.95).
综合的BPI截止值得分为41.25有效地识别了认知障碍.

结论:

这项研究为普通话说者提供了CBB的首次验证,证实了它对早期认知障碍查的可靠性.
该CBB可以提高及时的痴呆症诊断,并简化临床途径.
实施CBB解决了台湾医疗保健系统中痴呆症护理的关键需求.

关键词:

阿尔茨海默病 (AD) 是一种疾病.科格斯泰特短时间电池 (CBB)痴呆症是一种痴呆症.轻度认知障碍 (MCI) 是一种轻度认知障碍.台湾台湾台湾台湾

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