我们是否有足够的证据来推氧化酸盐牙膏预防牙损伤?
Neeraj Gugnani1, Shalini Gugnani2
1Department of Pedodontics and Preventive Dentistry, DAV (C) Dental College Yamunanagar, Yamunanagar, Haryana, India. drgugnani@gmail.com.
Evidence-based dentistry
|February 21, 2025
概括
与安慰剂相比,酸 (HAP) 牙膏显著预防牙,并显示出作为化物替代品的希望. 这一更新的系统性审查和元分析证实了HAP在牙科护理中的有效性.
科学领域:
- 牙科科学 牙科科学
- 牙 预防 预防 牙
- 生物材料是一种生物材料.
背景情况:
- 牙损仍然是一个重要的全球健康问题.
- 化物一直是预防虫的主要药物.
- 氧酸盐 (HAP) 正在作为一种替代性或辅助性预防剂进行探索.
研究的目的:
- 进行一次更新的系统审查和对酸预防虫病的临床证据的元分析.
- 为了比较HAP在预防虫方面的疗效与安慰剂和化物干预措施.
主要方法:
- 在多个电子数据库 (PubMed,Embase,Scopus,Web of Science,Google Scholar) 中采用了全面的搜索策略.
- 纳入标准包括临床试验和实地研究,研究HAP用于虫预防.
- 使用NHLBI标准进行了质量评估,并对来自18篇选定的文章的汇总数据进行了元分析.
主要成果:
- 与安慰剂牙膏相比,HAP牙膏在牙预防方面显示出显著更高的疗效 (合并OR=2.51).
- 虽然HAP牙膏有利于与化物牙膏进行比较 (合并OR=1.1),但这一结果在统计学上并不显著.
- 现场研究表明,HAP在减少病变深度和细菌负载方面具有显著的益处,对重矿化有无显著的积极影响.
结论:
- 酸 (HAP) 牙膏在预防牙损伤方面是有效的.
- 酸盐为化物提供了一个可行的,有效的替代方案,用于预防虫.
- 进一步的研究可能会巩固HAP在口腔卫生产品中与化物一起或作为化物的替代品的作用.
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