耐力训练对活跃的老年人退休年龄的脑灰质量没有长期益处
Mads Bloch-Ibenfeldt1, Naiara Demnitz2, Anne Theil Gates3
1Institute of Sports Medicine Copenhagen (ISMC), Department of Orthopedic Surgery M81, Bispebjerg and Frederiksberg Hospital, and Center for Healthy Aging, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. mads.bloch-ibenfeldt@regionh.dk.
BMC geriatrics
|February 21, 2025
概括
耐力训练没有改变老年人的大脑结构超过四年. 这项研究研究了重度或中度抵抗训练对老年人大脑体积变化的长期影响.
科学领域:
- 神经科学是一个神经科学.
- 老年学是指老年学的学科.
- 运动生理学 运动生理学
背景情况:
- 身体炼,包括阻力训练,经常被推用于大脑健康.
- 然而,它对老年人群大脑结构的具体影响仍然不清楚.
- 这项研究通过检查抗力训练对老年人大脑结构的影响来解决这一差距.
研究的目的:
- 研究一年的监督抵抗训练对老化中的大脑结构的短期和长期影响.
- 为了比较重力训练 (HRT) 与中等强度训练 (MIT) 对大脑变化的影响.
- 分析肌肉力量变化与大脑结构修改之间的关系.
主要方法:
- 在LISA研究中,随机选择了功能良好的老年人 (平均年龄66岁) 进入HRT,MIT或对照组.
- 大脑磁共振成像 (MRI) 在基线和1,2,4年随访时进行.
- 分析的重点是总灰质,海马体,dlPFC,vlPFC体积和白质超强度,将它们与肌肉强度变化相关联.
主要成果:
- 在所有组中,总灰质,海马体,vlPFC和dlPFC体积随着时间的推移而下降.
- 白质超强度体积在所有组都增加.
- 在4年期间,在抵抗训练组和对照组之间没有观察到大脑结构轨迹的显著差异.
结论:
- 在功能良好的老年人中,一年的力量训练在4年时间内没有显著地影响选择的大脑区域的体积变化.
- 研究结果表明,在研究的强度下,抵抗训练在这个人口群体中可能不会在这个时间范围内提供实质性的结构性大脑益处.
- 进一步的研究可能会探索不同的训练方案或人群,以阐明运动的潜在神经保护作用.
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