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Updated: May 26, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

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p53调节的SESN1和SESN2通过控制STAT3来调节细胞增殖和细胞死亡

Alexander Haidurov1, Andrei O Zheltukhin2, Anastasiya V Snezhkina2

  • 1School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Pearse Street, Dublin 2, Ireland.

Cell communication and signaling : CCS
|February 22, 2025
PubMed
概括

塞斯特林1和塞斯特林2 (SESN1&2) 蛋白调节细胞生长和活力. 通过通过PTPRD下调来激活STAT3,它们的非激活促进癌症,这表明SESN1&2的重新激活是癌症治疗.

关键词:
细胞死亡 细胞死亡肺癌是一种肺癌.在SESN1/2中使用.在STAT3中,我们可以使用STAT3.

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