暴露于和儿童的结果:系统性审查的概述
Lauren E O'Connor1, Maureen K Spill1, Rupal Trivedi1
1Texas A&M Agriculture, Food and Nutrition Evidence Center, Fort Worth, Texas, United States.
Environmental research
|February 22, 2025
概括
在怀孕和童年期间暴露于会给公众健康带来风险. 较高的含量与出生缺陷,多动症和儿童发育问题有关,需要进一步研究海鲜特定影响.
科学领域:
- 环境健康 环境健康
- 发育儿科 发育儿科
- 毒理学 毒理学 毒理学
背景情况:
- 在关键发育时期暴露于 (Hg) 是一个重大的公共卫生问题.
- 了解Hg对儿童发育的影响对于预防策略至关重要.
- 最近的系统审查是必要的,以综合目前关于Hg暴露和儿童结果的证据.
研究的目的:
- 系统地审查最近对暴露的系统审查 (SRs).
- 评估怀孕,哺乳期和童年期间暴露与儿童各种结果之间的关系.
- 识别知识缺口,特别是关于海鲜中的甲基.
主要方法:
- 搜索了三个电子数据库,查找2018年1月至2024年12月期间发表的SR.
- 包括SRs评估Hg暴露 (任何形式/来源) 在怀孕期间,哺乳期,或童年和儿童的结果 (例如,神经发育,多动症,自闭症,出生结果).
- 使用AMSTAR 2工具评估所包含的SRs的方法质量.
主要成果:
- 观察性研究的29个SRs被确定.
- 孕期暴露与出生缺陷,早产,多动症,自闭症和不良人体测量风险增加有关.
- 儿童暴露与ADHD风险更高,神经发育不良,生长和身体组成有关.
- 从海鲜中发现甲基的证据有限且不确.
结论:
- 在怀孕和童年期间暴露于是一种主要的公共卫生问题.
- 需要进一步的研究来了解海鲜中的甲基暴露.
- 需要更深入的理解来为未来的饮食建议和公共卫生政策提供信息.
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