在患有COVID-19的住院患者中AKI后的长期结果
Bernardo Marques da Silva1, Joana Gameiro1, Joana Lei Teixeira2
1Clínica Universitária de Nefrologia, Faculdade de Medicina da Universidade de Lisboa, Spain; Serviço de Nefrologia e Transplantação Renal, ULS Santa Maria, Spain.
Nefrologia
|February 22, 2025
概括
在COVID-19患者中,急性损伤 (AKI) 显著增加了长期问题和死亡率的风险. 早期识别和管理AKI对于改善患者的治疗结果和减少脏不良事件至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 急性损伤 (AKI) 是住院患者的常见并发症,与短期和长期预后不佳有关.
- COVID-19已与包括脏损伤在内的各种器官并发症有关,需要了解其长期脏影响.
- 在COVID-19住院期间的AKI与随后的脏不良事件和死亡率之间的关联需要进一步调查.
研究的目的:
- 评估COVID-19住院患者急性损伤 (AKI) 和长期不良结局之间的关联.
- 评估AKI对主要不良脏事件 (MAKE),主要不良脏心血管事件 (MARCE) 和两年随访期间死亡率的影响.
主要方法:
- 一项回顾性,单中心研究包括从2020年3月到10月在专用COVID-19病房住院的409名患者.
- 根据基于血清肌素 (SCr) 的病:改善全球结果 (KDIGO) 标准来定义和分阶段的AKI.
- 结果包括估计的淋巴细胞过率 (eGFR) 降低,需要脏替代疗法 (RRT),心血管事件和死亡率,评估时间为两年.
主要成果:
- AKI发生在60.4%的患者中. 在两年内,31.8%的人经历了eGFR下降,1.7%需要RRT,而27.9%的人死亡.
- 主要脏不良事件 (MAKE) 的发生率为60.9%,主要脏不良心血管事件 (MARCE) 的发生率为62.6%.
- 独立预测MAKE的因素包括老年,心血管疾病,慢性病和AKI. 高龄和瘤预测死亡率.
结论:
- 在COVID-19患者中,急性损伤独立地与长期功能下降,透析需要和死亡率的风险增加有关.
- 这些发现突显了AKI在COVID-19住院治疗的背景下长期存在的显著脏后果.
- 该研究强调了监测功能和管理AKI的重要性,以减轻COVID-19幸存者的长期不良结果.
关键词:
急性损伤是什么?急性损伤是什么?在 COVID-19 疫情中,节目 renales 敌人 敌人 大的.严重的功能衰竭 严重的功能衰竭长期的结果.主要的脏不良事件死亡率 死亡率死亡率 死亡率 死亡率一个长期的结果.更多相关视频
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