多感官刺激减少神经精神症状,增强老年痴呆症患者的认知功能:随机对照试验的元分析
Tiara Octary1, Melati Fajarini2, Hidayat Arifin3
1School of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan; School of Nursing, Politeknik Kesehatan Kementerian Kesehatan Pontianak, Indonesia.
The journal of prevention of Alzheimer's disease
|February 22, 2025
概括
多感官刺激有效地减少了老年痴呆症患者的焦虑,冷漠和抑郁,同时也改善了认知功能. 这种非药理学方法为管理痴呆症症状提供了一个有希望的治疗替代方案.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
背景情况:
- 多感官刺激 (MSS) 涉及多种感官,以提高老年人的幸福感.
- 它在治疗神经精神症状 (NPS) 和痴呆患者认知衰退方面的有效性需要进一步研究.
研究的目的:
- 通过元分析,评估多感官刺激在减少NPS和改善老年痴呆症患者认知功能的有效性.
主要方法:
- 在8个数据库中进行了系统搜索,截至2024年9月.
- 包括的研究涉及老年人 (65岁以上) 患有任何阶段的痴呆症.
- 使用随机效应模型计算聚合效应大小 (Hedge's g),评估异质性和出版偏差.
主要成果:
- 分析包括16项研究,涉及974名患者.
- 显著减少了激动 (g=-0.96),冷漠 (g=-1.27) 和抑郁 (g=-0.28) 的情况.
- 认知功能显著改善 (g=0.30),但焦虑没有显著变化 (g=-0.81).
- 兴奋,冷漠和焦虑方面注意到异质性;教育水平调节了兴奋效应.
结论:
- 多感官刺激显示出作为痴呆症非药物干预的潜力.
- 它可以有效地缓解NPS和增强认知功能,为临床实践提供一种有价值的治疗选择.
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