在第一波大流行期间,非传染性疾病的COVID-19阴性人群的过度死亡率
Daniel V Vigo1,2,3, Kristen L Hudec4, Saimoom Ferdous4
1School of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, BC, V6T 1Z3, Canada. daniel.vigo@ubc.ca.
BMC public health
|February 22, 2025
概括
在COVID-19的第一年,阴性测试的个体仍然面临着明显更高的死亡率. 这种与未经治疗的非传染性疾病 (NCD) 相关的间接过度死亡率远高于直接的COVID-19死亡率.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 估计COVID-19的间接死亡率对于疫情期间有效的公共卫生政策至关重要.
- 这项研究探讨了大流行病对健康的重大,但往往被忽视的间接影响.
研究的目的:
- 量化COVID-阴性队列在流行病的第一年期间的过度死亡率.
- 调查这种队列中先前存在的非传染性疾病 (NCD) 和死亡率之间的关联.
- 突出卫生保健服务中断对死亡率的影响.
主要方法:
- 利用全省范围的行政数据集来识别一组对COVID-19阴性测试的个人.
- 根据年龄,性别,非传染性疾病,多病症和敏度匹配了流行病前 (2018年) 队列.
- 采用双倍可靠的估计来评估大流行对死亡率的影响.
主要成果:
- 2020年COVID阴性个体与匹配的流行前对照人群相比,死亡几率高3.2倍.
- 死亡风险因非传染性疾病而异,未经治疗的非传染性疾病显示死亡几率增加了7倍.
- 在COVID-阴性队列中,过度死亡率表明最低间接过度死亡率为每10,000人中6.5.
结论:
- 在COVID阴性成年人中的死亡率在第一年大流行期间显著增加.
- 未诊断/未治疗的非传染性疾病的间接死亡率超过了COVID-19的直接死亡率.
- 强调需要在管理新的传染病原体的同时保持基本的医疗保健服务.
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