补充松树皮提取物可以改善心脏代谢风险因素吗? 一个系统的审查和元分析
Shooka Mohammadi1,2, Tamas Fulop3, Abdelouahed Khalil3
1Nutrition and Metabolic Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, 6135715794, Iran. shooka.mohammadi@gmail.com.
松树皮提取物 (PBE) 补充剂显著降低了包括血压,血糖和LDL胆固醇在内的关键心脏代谢风险因素. 这表明PBE可能是治疗心脏代谢综合征 (CMS) 的有益辅助疗法.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 代谢健康 代谢健康
背景情况:
- 心脏代谢综合征 (CMS) 涉及多种影响心血管和代谢健康的风险因素.
- 松树皮提取物 (PBE) 是一种对管理这些风险因素具有潜在益处的补充剂.
研究的目的:
- 系统地审查和元分析随机对照试验 (RCT),评估PBE补充对心脏代谢风险因素的影响.
- 确定PBE作为CMS辅助疗法的疗效.
主要方法:
- 一个全面的文献搜索确定了相关的RCT,直到2024年9月.
- 使用随机效应模型对27项涉及1685名参与者的RCT数据进行了元分析.
主要成果:
- 服用PBE补充剂显著降低了系统血压 (SBP),透气血压 (DBP),禁食血糖 (FBS),HbA1c,体重和LDL胆固醇.
- 在腰与部比 (WHR),体重指数 (BMI),腰围 (WC),胰岛素,高密度胆固醇,甘油三 (TG) 或总胆固醇 (TC) 上没有发现显著影响.
结论:
- 补充PBE显示了改善特定心脏代谢风险因素的潜力,如SBP,DBP,FBS,HbA1c,体重和LDL胆固醇.
- PBE可以作为管理CMS的辅助治疗策略.
- 需要进一步进行高质量,大规模和长期的试验来证实这些发现.
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