在怀孕期间母亲的贫血与婴儿出生体重低之间的关联
Rozhan Khezri1, Fatemeh Rezaei2, Shayesteh Jahanfar3
1Student Research Committee, Iran University of Medical Sciences, Tehran, Iran. khezri.rojan@yahoo.com.
Scientific reports
|February 22, 2025
概括
怀孕期间母亲的贫血,在第一和第二个三个月的低血红蛋白水平表明,显著增加低出生体重的风险. 早期发现和治疗贫血对于改善妊娠结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 低出生体重 (LBW) 和贫血是关键的全球健康问题,特别是在发展中国家.
- 怀孕期间的贫血对母亲和胎儿的健康构成重大风险.
- 孕妇COVID-19感染可能会影响怀孕的结果.
研究的目的:
- 调查母亲在第一和第二个三个月的血红蛋白水平与低出生体重的发生率之间的联系.
- 评估妊娠早期和中期贫血对胎儿生长的影响.
- 为了确定COVID-19的孕妇出生体重低的危险因素.
主要方法:
- 一项涉及385名伊朗COVID-19的孕妇的多中心,横截面研究.
- 血红蛋白水平在第一个 (6-10周) 和第二个 (24-28周) 三季度被测量.
- 使用多变量逻辑回归分析来确定血红蛋白水平与低出生体重之间的关联,并对混因素进行调整.
主要成果:
- 第一个季度低血红蛋白水平 (<110 g/L) 与低出生体重显著相关 (OR,4.13;95% CI 2.11-8.10).
- 第二个三个月低血红蛋白水平 (<105 g/L) 也显示出与低出生体重有显著的关联 (OR: 3.91; 95% CI: 1.98-7.75).
- 在调整了混杂因素后,母亲在两季度的贫血仍然是低出生体重的重要预测因素.
结论:
- 怀孕期间的母体贫血是低出生体重的重要危险因素,即使在COVID-19的妇女中也是如此.
- 对孕妇贫血的监测和有效管理是预防低出生体重的重要干预措施.
- 这些发现强调了在低收入和中等收入国家解决贫血问题的重要性,以改善母亲和儿童健康结果.
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