新生儿三胞胎形状13的医院护理的变化
Allison O Ignatz-Hoover1, Mohsen A A Farghaly2,3, Anna Crist1
1Neonatal Intensive Care Unit, Cleveland Clinic Children's Hospital, 9500 Euclid Avenue #M31, Cleveland, OH, 44195, USA.
Maternal and child health journal
|February 22, 2025
概括
新生儿存活率对于Trisomy 13的婴儿保持不变,死亡率没有显著变化. 然而,住院时间显著增加,特别是在气管切除和G管安置等干预措施下.
科学领域:
- 新生儿科学 新生儿科学
- 遗传学 遗传学 是一个
- 儿科手术 儿科手术
背景情况:
- 三胞胎症13 (Patau综合征) 是一种严重的遗传疾病,与高新生儿死亡率有关.
- 了解三胞胎症13婴儿的护理趋势和结果对于改善管理至关重要.
研究的目的:
- 分析新生儿存活率的趋势,不良事件,外科手术,气管/胃口管 (G-管) 放置,以及三胞胎13的婴儿的停留时间 (LOS).
- 为了确定2003-2018年期间这些结果的变化.
主要方法:
- 对2003-2018年国家住院样本数据库的回顾性分析.
- 包括被诊断患有三胞胎形状13的新生儿
- 检查生存率,不良事件,手术 (气管,G管) 和LOS,并进行趋势分析.
主要成果:
- 总共有5792名患有三胞胎形状13的婴儿被确定.
- 住院新生儿死亡率为58%,在研究期间没有显著变化.
- 平均LOS显著增加 (p < 0.001),在患有NEC,GI异常和败血症的婴儿中最高. 2%的幸存者通过气管切除术出院,9%的人使用G管.
结论:
- 在医院的新生儿死亡率对于Trisomy 13的婴儿没有改变.
- 有显著的LOS增加,与气管切除术和G管安置等手术相关.
- 这表明增加干预的趋势,而没有对Trisomy 13婴儿的生存率相应的改善.
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