胎儿双侧过高性脏:产前进展和长期产后结果
Kavyesh Vivek1, Sandra Subtil2, Elisabetta Sanna3
1Department of Surgery and Cancer, Imperial College London, London, UK.
Early human development
|February 23, 2025
概括
胎儿双侧高性脏 (HK) 具有正常的胎液指数 (AFI) 通常具有良好的预后和正常的功能. 然而,建议长期跟踪,特别是对于那些有遗传疾病的人来说.
科学领域:
- 产周医学 产周医学
- 胎儿医学 胎儿医学
- 儿科病学 儿科病学
背景情况:
- 双边高性脏 (HK) 是一个产前发现,结果各不相同.
- 了解胎儿HK的进展和长期预后对于临床管理至关重要.
研究的目的:
- 为了确定胎儿双边高性脏 (HK) 的产前进展和长期结果.
主要方法:
- 从2005年至2016年对胎儿/母亲人口统计,扫描结果和产后诊断的回顾性研究.
- 对结局的分析,包括存活率,HK的解决和长期功能.
主要成果:
- 在大多数情况下,与正常胎液指数 (AFI) 隔离的HK具有96%的存活率和正常的功能.
- 降低HK胎儿的AFI表明预后不佳,仅有5%的存活率.
- 长期随访显示,在74%的病例中,HK已经消失;持续的HK与遗传条件有关,例如HNF1b/17q12删除病.
结论:
- 隔离的胎儿HK与正常的AFI通常导致生存和正常的功能,但由于潜在的遗传倾向,建议长期监测.
- 胎儿HK与oligohydramnios (减少的AFI) 携带一个显着糟糕的预后.
- 总体生存率在第一年为38%,长期为34%,这凸显了仔细评估和随访的重要性.
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