通过基于废水的流行病学估计公众暴露于PAH和环境风险
Katarzyna Styszko1, Justyna Pamuła2, Elżbieta Sochacka-Tatara3
1AGH University of Krakow, Faculty of Energy and Fuels, Kraków, Poland.
Ecotoxicology and environmental safety
|February 23, 2025
概括
基于废水的流行病学 (WBE) 可以使用氧化PAH (OH-PAH) 生物标志物监测多环芳 (PAH) 暴露. 这项研究显示OH-PAH水平和暴露的季节性变化,冬季观察到的度和风险更高.
科学领域:
- 环境科学 环境科学
- 公共卫生 公共卫生
- 分析化学 分析化学
背景情况:
- 基于废水的流行病学 (WBE) 提供了一个强大的工具,通过尿路生物标志物分析监测公共卫生紧急情况.
- 多环芳 (PAH) 是广泛存在的环境污染物,具有潜在的健康风险.
- 氧化PAH代谢物 (OH-PAH) 作为可靠的生物标志物用于评估人类的暴露.
研究的目的:
- 开发和应用一种新的WBE方法,用于使用特定的OH-PAH生物标志物进行PAH暴露的空间和时间评估.
- 量化原始和经过处理的废水中的OH-PAH度,并评估其去除效率.
- 估计人类每日接触OH-PAHs,并评估相关的环境风险.
主要方法:
- 在废水样本中分析目标OH-PAHs (1-氨酸,2-氨酸,2-氨酸,9-氨酸,9-氨酸,1-氨酸和3-氨酸).
- 在原始污水中量化OH-PAH总负载,并确定废水处理过程中的去除效率.
- 根据急性和慢性毒性数据,对人类OH-PAH吸收的逆向计算和风险系数 (RQ) 的计算.
主要成果:
- 大多数目标OH-PAH在原始和经过处理的废水中都检测到可量化的水平.
- 原始污水中的OH-PAH总负荷呈季节性变化,冬季的负荷比夏季更高.
- OH-PAHs的去除效率取决于季节,冬季 (一月) 的降解率高于夏季 (八月).
- 人均估计的每日OH-PAH吸收量在冬季 (每天4.1微克) 比夏季 (每天2.1微克) 高,与文献价值保持一致.
- 风险系数 (RQ) 表示1月风险较低,8月风险较高,这表明夏季由于废水度和含量增加,环境和健康问题增加.
结论:
- 本研究提出了首个废水中OH-PAHs的分析,用于评估PAH暴露,并评估它们的去除和排放.
- 使用OH-PAHs的WBE提供了一种有价值的方法,用于监测具有明显季节性模式的PAHs对人口水平暴露.
- OH-PAH清除效率和废水度的季节性变化凸显了环境监测计划中需要具体环境风险评估的需要.
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