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Updated: May 26, 2025

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

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在LacI的静态位置52的替换对LacI形状景观有远程影响

Nilusha L Kariyawasam1, Anastasiia Sivchenko2, Liskin Swint-Kruse2

  • 1Department of Chemistry, 213 CBC Building, 1212 Mid-Campus Dr. North, Kansas State University, Manhattan, KS 66506, USA.

Biophysical chemistry
|February 23, 2025
PubMed
概括

氨基酸替代在蛋白质修态位上通过改变形状景观而改变功能. 一项对大肠杆菌LacI的研究表明,特定的V52替代物极大地改变了蛋白质构造,改变了全调节,并验证了这一机制.

关键词:
结合 DNA 的 DNA 结合.水定压力压力是水定压力.这是一种 LacL 蛋白质.分子动力学模拟的模拟.蛋白质的构造结构.

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