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Updated: May 11, 2026

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开发氨酸和氨酸相关的混合分子,作为SHP1光激活剂的新型类别

Xu-Yang Mu1, Li-Xin Gao2, Zhen-Xuan Zhang3

  • 1School of Life Sciences and Health Engineering, Jiangnan University, Wuxi, 214122, China; School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122, China.

European journal of medicinal chemistry
|February 23, 2025
PubMed
概括

研究人员开发了针对SHP1的新型光激活剂,这是细胞过程中的关键蛋白质. 化合物3n证明了SHP1激活和抑制癌细胞增殖,显示了生物成像应用的潜力.

关键词:
细胞成像 细胞成像库马林 - 普洛卡因混合分子分子.光有机分子的光有机分子.在 SHP1 中, SHP1 是 SHP1.对SHP1同类蛋白质的选择性

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