普罗西亚尼丁B2通过抑制TLR4/NF-κB和caspase-3/GSDME通路来减轻甲基甲酸诱导的肝炎

Juman Alsaab1, Wedad S Sarawi1, Ahlam M Alhusaini1

  • 1Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 22452, Riyadh, 11495, Saudi Arabia.

概括

普罗基亚尼丁B2 (PCB2) 显示出对甲基酸 (MTX) 诱导的肝损伤的保护作用. PCB2表现出抗氧化,抗炎和抗火性质,减轻了老鼠的MTX毒性.

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