基于酵母的人类甲状腺激素受体记者基因测试的实验室内验证

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Masahiro Ogawa1, Junya Kitamoto2, Mayuko Nakashima3

  • 1Life Science Research Institute, Kumiai Chemical Industry Co., Ltd, 3360 Kamo, Kikugawa-shi, Shizuoka 439-0031, Japan; Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, Gakuen-cho 1-2, Naka-ku, Sakai, Osaka 599-8570, Japan.

Journal of pharmacological and toxicological methods
|February 23, 2025
PubMed
概括

经过验证的基于酵母的测试准确地检测出甲状腺激素被化学物质破坏的情况. 这些具有成本效益的,不使用动物的记者基因测试提供了使用光基质进行甲状腺受体交换活化分析的改进检测.

关键词:
内分泌干扰的化学物质破坏内分泌.记者基因测试试验甲状腺激素是甲状腺激素的一种.基于酵母的生物测试.

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