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Updated: May 26, 2025

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CCCTC-结合因子N-终端域通过增强凝聚过程性来调节聚类原cadherin基因表达

Yijun Zhang1, Qiang Wu1

  • 1Center for Comparative Biomedicine, Ministry of Education Key Laboratory of Systems Biomedicine, State Key Laboratory of Medical Genomics, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China.

The Journal of biological chemistry
|February 23, 2025
PubMed
概括

CCCTC结合因子 (CTCF) 增强了凝聚素挤出DNA循环的能力,这是3D基因组折叠的关键过程. 这一发现挑战了关于CTCF在基因组组织中的作用的传统观点.

关键词:
在 CTCF YDF 图案中.聚类的原始cadherin.凝聚力进程性 凝聚力进程性增强剂-促进剂相互作用.基因调节 基因调节 基因调节循环挤出循环的挤出.

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