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Updated: May 26, 2025

Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems
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Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems

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使用基于平台的质谱检测的mRNA疫苗的功能和翻译忠实性表征

Alyssa Q Stiving1, Benjamin W Roose2, Christopher Tubbs2

  • 1Analytical Research & Development, Merck & Co., Inc, 126 E Lincoln Ave., Rahway, NJ, USA. alyssa.stiving@merck.com.

NPJ vaccines
|February 23, 2025
PubMed
概括

一种新的无细胞翻译和质谱法准确地检测和量化mRNA编码的蛋白质. 这个平台识别了非目标框架转移,并评估了mRNA疫苗的质量.

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