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Updated: May 26, 2025

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从氨基酸单体能量景观中解码可溶性特征

Patryk Adam Wesołowski1, Bojun Yang2, Anthony J Davolio3

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.

Journal of chemical theory and computation
|February 24, 2025
PubMed
概括

研究人员探索了粉样单体能量格局,以了解阿尔茨海默病蛋白质错折. 他们确定了特定的结构特征,如暴露的疏水性残留物,与降低溶解度和容易聚合的状态有关.

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