针对性短波透皮术与认知训练相结合,用于患有严重创伤性视神经病变的患者
Qingping Tang1, Hua Zhang2, Huayang Deng1
1Department of Rehabilitation, Brain Hospital of Hunan Province, Hunan University of Chinese Medicine, Changsha, Hunan, China.
European journal of ophthalmology
|February 24, 2025
概括
有针对性的短波透视 (SWD) 和感知训练显著改善了严重创伤性视神经病变 (TON) 患者手术后的视觉功能. 这种联合康复提供了恢复视力的希望,即使在长期视力丧失后也是如此.
科学领域:
- 眼科医生 眼科 眼科
- 神经学 神经学
- 康复医学 康复医学 康复医学
背景情况:
- 严重的创伤性视神经病变 (TON) 往往导致视力有限的改善,尽管治疗.
- 内镜视神经减压 (EOND) 手术用于TON,但视觉恢复可能是不理想的.
研究的目的:
- 评估针对性短波透视 (SWD) 与感知训练相结合的有效性,以提高EOND手术后严重TON患者的视觉功能.
主要方法:
- 40名患有EOND后严重TON的患者随机分配到康复 (Reh) 组 (n=24) 或非康复 (Nreh) 组 (n=16).
- 雷赫组接受了针对性的SWD治疗和16周的感知训练.
- 视觉功能,视觉唤起潜力 (VEP) 和扩散张力成像 (DTI) 被评估.
主要成果:
- 与Nreh组相比,Reh组在最佳校正的视敏度 (p=0.006) 和彩色视觉得分 (p=0.026) 中显著改善.
- 两名儿童在康复后恢复了视力敏度 (≤1.0 logMAR),即使在TON后62天和73天完全视力丧失.
- 在10周后,Reh组在受影响的视神经中显示出明显更高的P100平均振幅 (p=0.012) 和分数异质性 (p=0.032对前部,p=0.014对中间部分).
结论:
- 针对性SWD与感知训练相结合,对EOND手术后严重TON的患者有益.
- 这项研究提供了第一个证据表明,通过综合康复,在完全视力丧失73天后,TON儿童的视力功能恢复.
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