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Updated: Jun 26, 2026

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微RNA-203表达作为狼性炎的潜在生物标志物

Yuswanto Setyawan1,2, Hani Susianti3, Hermin Sulistyarti3

  • 1Doctoral Program in Biomedical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.

International journal of nephrology and renovascular disease
|February 24, 2025
PubMed
概括

与系统性红斑狼 (SLE) 患者相比,MICRORNA-203在狼性炎 (LN) 患者中表达的更高. 这一发现表明microRNA-203可能作为诊断SLE炎的潜在生物标志物.

关键词:
狼性炎是一种神经炎症.微型RNA-203是什么意思系统性红血性狼 (Systemic Lupus Erythematosus) 是一种全身性狼.

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...