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Updated: May 26, 2025

Real-Time Quantification of the Effects of IS200/IS605 Family-Associated TnpB on Transposon Activity
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Published on: January 20, 2023

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突变扫描揭示了TnpB中的潜活动

Brittney W Thornton1,2, Rachel F Weissman1,2, Ryan V Tran3,4

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, 94720, USA.

bioRxiv : the preprint server for biology
|February 24, 2025
PubMed
概括

研究人员通过发现其蛋白质和RNA组件中的激活突变来增强RNA引导的内核酶TnpB活性. 这一突破显著提高了人类细胞和植物的基因组编辑潜力.

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