在中部和侧部前额叶皮层中,主动和反应性认知控制的神经动态
Anas U Khan1, Colin Hoy2,3, Kristopher L Anderson3
1Department of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL, USA.
bioRxiv : the preprint server for biology
|February 24, 2025
概括
认知控制包括对冲突做出反应并为冲突做好准备. 这项研究发现,dorsomedial前额叶皮层 (dmPFC) 的theta振荡信号主动控制,而dmPFC和dorsolateral前额叶皮层 (dlPFC) 在冲突适应过程中显示出不同的神经动态.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 计算神经科学是一种神经科学.
背景情况:
- 认知控制可以通过管理冲突来实现目标导向的行为.
- 背中介前额叶皮层 (dmPFC) 和背侧前额叶皮层 (dlPFC) 通过theta振荡和人口活动参与反应性控制.
- 积极主动控制或预测冲突的神经机制仍然不太了解.
研究的目的:
- 为了研究预期冲突时主动控制和行为适应的神经基础.
- 通过使用内EEG (iEEG) 检查dmPFC和dlPFC在认知控制中的作用.
- 为了区分支持反应与主动控制策略的神经动力学.
主要方法:
- 在人类参与者执行Stroop任务时,利用dmPFC和dlPFC的iEEG记录.
- 操纵跨区块的冲突频率,以引起主动和反应性控制需求.
- 分析了与冲突预测和处理有关的theta振荡,高频活动 (HFA) 和β频段功率.
主要成果:
- 在dmPFC和dlPFC中观察到dmPFC和HFA的冲突引起的增加,与反应性控制相一致.
- 在两个区域中确定了与冲突相关的响应后的theta抑制,dlPFC中响应前的β脱同步以及响应后的β反弹.
- 在预期冲突时,在试验前发现dmPFC乙太功率增加,作为主动控制标记.
- 证明与冲突相关的theta,beta和HFA信号由冲突频率调节,在罕见的冲突中增强,在常见的冲突中减少.
结论:
- 在反应冲突处理过程中,dmPFC和dlPFC存在共享的高频活动 (HFA),但不同的振荡动态.
- 试验前的dmPFC太功率成为主动认知控制的关键神经基质.
- 这些发现完善了对dmPFC和dlPFC在根据预期的冲突水平调整认知控制中的作用的理解.
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