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综合应激反应的血统可塑性是癌症进化的一个标志

Shiqi Diao, Jia Yi Zou, Shuo Wang

    bioRxiv : the preprint server for biology
    |February 24, 2025
    PubMed
    概括

    综合应激反应 (ISR) 通过促进可塑性和干性来驱动癌症脱差和治疗耐药性. 抑制ISR信号阻断了肺癌模型中的瘤生长和线粒体功能障碍.

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