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Updated: Apr 30, 2026

Assessing Cerebral Autoregulation via Oscillatory Lower Body Negative Pressure and Projection Pursuit Regression
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TDP-43 聚合物播种破坏自我调节并导致 TDP-43 功能障碍

Lohany Dias Mamede1, Miwei Hu2, Amanda R Titus1

  • 1Edward Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis MO 63104, USA.

bioRxiv : the preprint server for biology
|February 24, 2025
PubMed
概括

在神经退行性疾病中,TDP-43聚合导致其错位和功能丧失. 破坏TDP-43自我调节会放大这种有毒聚合过程,可能导致疾病病理.

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