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Updated: May 26, 2025

Analyzing and Building Nucleic Acid Structures with 3DNA
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迪克尔酶功能的生物化学和结构基础通过复活古老蛋白质而揭示

Adedeji M Aderounmu1, Josephine Maus-Conn1, Claudia D Consalvo1

  • 1Department of Biochemistry, University of Utah, Salt Lake City, Utah 84112 USA.

bioRxiv : the preprint server for biology
|February 24, 2025
PubMed
概括

祖先的Dicer螺旋酶进化减少了dsRNA结合和转位,影响了抗病毒防御. 重建的古代酶揭示了ATP水解是如何在dsRNA沿线驱动运动的,解释了现代的Dicer多样性.

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