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Updated: May 26, 2025

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分子引导的空间蛋白质组学捕捉了单细胞的身份和神经系统的异质性

Sayan Dutta1,2, Marion Pang1, Gerard M Coughlin1,2

  • 1Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125.

bioRxiv : the preprint server for biology
|February 24, 2025
PubMed
概括

空间单细胞蛋白质组学揭示了中枢神经系统和外周神经系统中的蛋白质组差异. 这种技术通过分析组织异质性和神经系统疾病来推进神经科学研究.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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