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Updated: May 26, 2025

Preparation of Contiguous Bisaziridines for Regioselective Ring-Opening Reactions
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Published on: July 28, 2022

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尼塔衍生物在μ-阿片类受体的假定结合模型

Joseph Clayton1,2, Lei Shi3, Michael J Robertson4

  • 1Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD 20993, USA.

bioRxiv : the preprint server for biology
|February 24, 2025
PubMed
概括

计算模拟揭示了称为尼塔的强有力的合成阿片类药物如何与mu-opioid受体 (μOR) 结合. 尼塔可能有利于特定的结合模式,为阿片类受体相互作用提供了洞察力,并指导了未来的药物设计.

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