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Updated: May 26, 2025

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme
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Published on: April 12, 2013

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在 orofacial 裂病因学的遗传-表观遗传相互作用 (meQTLs)

L A Machado-Paula1, J Romanowska2, R T Lie2

  • 1University of Iowa College of Dentistry and Dental Clinics, Iowa City, IA, USA.

medRxiv : the preprint server for health sciences
|February 24, 2025
PubMed
概括

这项研究表明,遗传变异通过改变DNA甲基化模式来影响面腔裂 (OFCs) 风险. 这些表观遗传变化影响基因表达,有助于解释OFC中缺失的遗传性和可变表达性.

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