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Updated: May 26, 2025

Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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DNMT3a通过激活HDAC7信号通路来促进LUAD细胞的增殖和转移

Menglong Jiang1, Xin Zhou2,3, Yingtong Feng4

  • 1Department of Thoracic Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.

International journal of biological sciences
|February 24, 2025
PubMed
概括

基因组甲基转移酶3α (DNMT3a) 通过上调基因素脱乙酶7 (HDAC7),ZEB1和c-Myc的调节,促进肺腺癌 (LUAD) 的进展. 针对DNMT3a和HDAC7可能为LUAD患者提供新的治疗策略.

关键词:
在 DNMT3a 中使用.在HDAC7中,HDAC7是指HDAC7.卢阿德 (Luad) 的意思是说.在ZEB1中,ZEB1是指ZEB1.c-Myccc 的意思是我的

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