评估确定脉冲波速度的计算机算法的有效性:一项临床研究
Amira Tairi1, Hasan Obeid2, Saliha Addour2
1Division of Nephrology, Department of Medicine, CHU de Québec-Université Laval Research Center, Faculty of Medicine, Université Laval, Québec City, QC, Canada.
Pulse (Basel, Switzerland)
|February 24, 2025
概括
该研究发现,用于计算脉冲波速度 (PWV) 的第二导数和交叉触点算法在结果中产生了微不足道的差异. 这表明没有必要根据用于脉冲过渡时间的算法调整PWV测量.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
- 医学诊断 医学诊断 医学诊断
背景情况:
- 大动脉硬度,通过带-大腿脉冲波速率 (PWV) 测量,是心血管疾病的一个关键风险因素.
- 精确的PWV测量依赖于精确识别脉冲波形脚.
- 现有的方法,如第二导数和交叉触点算法,可以产生不同的PWV结果.
研究的目的:
- 为了比较脉冲过渡时间 (PTT) 和PWV,使用第二导数和交叉触点算法计算.
- 当两个算法处理相同的输入信号时,评估差异.
主要方法:
- 通过使用MATLAB分析了来自113名受试者的3,770对过的脉冲波.
- 使用第二导数 (PTTMat-2nd,PWVMat-2nd) 和交叉触点 (PTTMat-IT,PWVMat-IT) 算法计算了PTT和PWV.
- 与Complior (PWVComp-2nd) 和SphygmoCor (PWVSphyg-IT) 系统进行了比较结果.
主要成果:
- 平均PTT值几乎相同:54.55±18.55毫秒 (第二导数) 与54.61±18.61毫秒 (交叉触线).
- 平均PWV值显示了最小的差异:MATLAB算法之间的0.01±0.32米/秒 (PWVMat-2nd与PWVMat-IT).
- 针对特定设备的算法之间的差异也很小:0.11 ± 0.66 m/s (PWVComp-2nd与PWVSphyg-IT).
结论:
- 用第二导数和交叉触点算法计算的PWV差异是可以忽略不计的.
- 基于用于PTT确定的算法进行PWV测量时不需要调整.
- 这一发现简化了在不同的分析方法中解释PWV测量.
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