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Updated: May 26, 2025

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香烟吸烟诱导了小鼠的骨肌肉缩,通过激活的巨介导的灭

Yufen Tan1, Yuanyuan Ye1, Cuibi Huang1

  • 1Department of Respiratory and Critical Care Medicine, the second Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.

Journal of inflammation research
|February 24, 2025
PubMed
概括

暴露在香烟烟雾 (CS) 中会通过激活巨细胞和热症导致骨肌肉缩. 巨细胞衍生的TNF-α通过TNFR1/NLRP3/caspase-1/GSDMD通路启动这个过程,导致COPD相关的肌肉衰竭.

关键词:
慢性阻塞性肺病 慢性阻塞性肺病香烟的烟雾,就是烟雾.巨细胞是什么?巨细胞是什么?热致灭 (pyroptosis) 是一种致的过程.骨肌肉缩 骨肌肉缩

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