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肌肉内注射rAAV2-retro用于低运动神经元转导:评估五种促进剂

Xueqi Gong1,2, Haitong Gao1,2, Wenyuan Wang3,4

  • 1Laboratory Animal Center, Fudan University, Shanghai 200032, China.

International journal of medical sciences
|February 24, 2025
PubMed
概括

再组合腺相关病毒载体 (rAAVs) 有效地将基因传递到脑干和脊髓的下部运动神经元 (LMN). CAG和hCMV促进体显示出最高的基因表达,而不会引起毒性,优化了对运动神经元疾病的基因传递.

关键词:
基因治疗的基因疗法灯光板 - 灯光板 - 灯光板运动神经元 运动神经元活动主办人 活动主办人rAAV2-复古的 rAAV2-复古的 rAAV2-复古的

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