内静脉诱导静脉血栓形成:单一中心的结果和元分析
Nedaa Skeik1,2, Kiahltone Thao2, Rami Musallam3
1Section of Vascular and Endovascular Surgery Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, USA.
Angiology
|February 24, 2025
概括
化学粘合物闭合 (CAC) 对于慢性静脉功能不充分是有效的,内静脉粘合物诱导的血栓形成 (EGIT) 很少发生在1.2%. 在审查的研究中,这种并发症与深静脉血栓或肺栓塞没有显著的关联.
科学领域:
- 血管外科 血管外科
- 医疗器械技术 医疗器械技术
- 血栓形成研究研究
背景情况:
- 化学粘性封闭 (CAC) 为慢性静脉功能不全 (CVI) 提供了热除的替代方案,使患者恢复得更快.
- 静脉内粘剂诱导的血栓形成 (EGIT) 是一种已知的,但很少报告的CAC的并发症.
- 关于EGIT的患病率及其与深静脉血栓塞 (DVT) 和肺栓塞 (PE) 相关的数据有限.
研究的目的:
- 为了确定EGIT在CAC之后的综合流行率.
- 调查EGIT,DVT和PE之间的潜在关联.
- 为了评估接受CAC.患者EGIT的风险因素.
主要方法:
- 用CAC治疗的患者的回顾性图表分析 (2018年1月 - 2022年5月).
- 对报告EGIT案例的研究进行全面的文献搜索 (PubMed/Medline,Embase,Cochrane).
- 数据综合,包括聚合流行率计算和风险因素分析.
主要成果:
- 在19项研究 (2101名患者) 中,EGIT的综合患病率为1.2% (95%CI:0.3%-2.1%).
- 报告了两例CAC相关的DVT病例;没有确定相关的PE病例.
- 在机构队列中,患者人口统计学,静脉特征或程序复杂性与EGIT风险之间没有发现显著的关联.
结论:
- CAC是CVI的有效治疗方法,EGIT的流行率很低.
- EGIT是一种罕见的并发症,目前的数据表明,相关的DVT和PE的风险很低.
- 进一步的研究可能会阐明EGIT在CAC程序中的特定风险因素.
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