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Updated: May 26, 2025

Electromechanical Assessment of Optogenetically Modulated Cardiomyocyte Activity
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Electromechanical Assessment of Optogenetically Modulated Cardiomyocyte Activity

Published on: March 5, 2020

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调节心肌细胞收缩性和动作潜力,使用化学基因化物流

Muhammed Sönmez1,2, Tim Stüdemann1,2, Christoph Manthey1,2

  • 1Institute of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

The Journal of physiology
|February 24, 2025
PubMed
概括

药理选择性执行模块 (PSAM) 是设计的离子通道,可以控制细胞活动. 这项研究表明,PSAM-GlyR和PSAM4-GlyR可以通过调节化物电流来逆向抑制心肌细胞功能.

关键词:
心脏电生理学心脏电生理学心脏功能是指心脏功能.这是心肌细胞 (cardiomyocyte).化学遗传学 化学遗传学多能干细胞是一种多能干细胞.

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