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Updated: Jul 16, 2026

A Microscopic Phenotypic Assay for the Quantification of Intracellular Mycobacteria Adapted for High-throughput/High-content Screening
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揭示阿斯科布酸对M.结核病的特性通过in silico方法:一种基于药物的比较研究

Aviral Kaushik1, Arti Peshrana1, Rohit Barapatre1

  • 1Department of Life Sciences, Parul Institute of Applied Sciences and Biophysics & Structural Biology Laboratory, Research & Development, Cell, Parul University, Vadodara, Gujarat, India.

Journal of molecular modeling
|February 24, 2025
PubMed
概括

亚酸 (维生素C) 显示出作为一种新的结核病治疗的潜力. 在的研究表明,它可以抑制Mycobacterium结核病途径,提供一种新的策略来对抗耐药结核病.

关键词:
结核病菌菌菌的结核病菌的结核病菌.亚斯科布酸是一种亚斯科布酸.药物耐药性 药物耐药性 药物耐药性分子对接是分子对接.分子动力学模拟模型

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Inhibitors of Bacterial Protein Synthesis01:25

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Aminoglycosides constitute a highly potent class of bactericidal antibiotics that exert their antimicrobial effects by targeting the bacterial ribosome, specifically disrupting protein synthesis. These polycationic molecules consist of amino-modified sugars linked via glycosidic bonds to an aminocyclitol core such as 2-deoxystreptamine or streptamine. Their strong positive charges facilitate tight binding to the negatively charged phosphate backbone of ribosomal RNA (rRNA), primarily at the 16S...