的营养状况和甲状腺功能障碍
Luciana Sant'Ana Leone de Souza1,2, Renata de Oliveira Campos1,2,3, Jair de Souza Braga1
1Departamento de Biorregulação, Instituto de Saúde e Ciências, Universidade Federal da Bahia, Salvador, BA, Brasil.
Archives of endocrinology and metabolism
|February 24, 2025
概括
(Se) 对甲状腺健康至关重要,支持抗氧化功能和激素代谢. 缺乏与甲状腺疾病有关,但需要更多的研究来确认补充的益处.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 免疫学 免疫学 免疫学
背景情况:
- (Se) 是一种重要的微量营养素,对免疫和调节功能至关重要.
- 在甲状腺组织中,Se是抗氧化剂系统和神酶的组成部分,影响甲状腺激素代谢.
- 低Se水平会损害谷氨过氧化酶的活性,增加氧化应激和甲状腺损伤.
研究的目的:
- 审查目前对在甲状腺病理生理学中的作用的理解.
- 探索状况与各种甲状腺疾病之间的关联.
- 评估补充剂对甲状腺健康的潜在益处.
主要方法:
- 现有文献的叙述性审查.
- 在PubMed,Lilacs和SciELO数据库中进行文献搜索.
- 对调查含量和甲状腺疾病的研究进行分析.
主要成果:
- 缺乏与生长迟缓,生殖问题,Keshan病和Kashin-Beck病有关.
- 血清Se水平与轻度Se缺乏地区的自身免疫性甲状腺炎之间存在逆相关性.
- 补充可能有助于实现euthyroidism和改善Graves病的结果.
结论:
- 保持足够的水平可能与预防甲状腺疾病有关.
- 有证据表明,在控制自身免疫性甲状腺炎和格雷夫斯病方面起着作用.
- 需要进一步的研究来确定补充剂对甲状腺健康的有效性.
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