在OSCC中免疫疗法:当前的趋势和挑战
Shalini Gupta1, Akanchha Singh1, Sakshi Deorah1
1Department of Oral Pathology and Microbiology, King George's Medical University, Lucknow 226003, India.
Critical reviews in oncology/hematology
|February 24, 2025
概括
免疫疗法显示出作为口腔癌治疗的第四支柱的承诺,补充化疗,放射和手术. 需要进一步的研究来克服挑战,并改善口腔状细胞癌患者的治疗结果.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 头部和部癌症 头部和部癌症
背景情况:
- 口腔癌是一种普遍存在的头恶性瘤.
- 目前的治疗方法包括化疗,放射和手术.
- 免疫疗法成为癌症治疗的潜在第四支柱.
研究的目的:
- 为口腔状细胞癌 (OSCC) 概述免疫治疗原则.
- 审查在OSCC治疗中使用的各种免疫治疗药物.
- 突出免疫疗法作为单疗法或辅助治疗的作用.
主要方法:
- 在PubMed,Scopus和谷歌学者中进行全面的文献搜索.
- 包括英语和非英语文章,重点关注高发病率的国家.
- 两位盲目的病理学家收集和审查数据.
主要成果:
- 该手稿汇编了数据,为OSCC提供了有关当前免疫治疗趋势的见解.
- 免疫疗法可以作为单一疗法或辅助治疗有益.
- 由于依赖患者的免疫环境,患者的选择至关重要.
结论:
- 需要进行先进的研究来应对OSCC中的免疫治疗挑战.
- 免疫疗法在改善口腔癌患者治疗方面具有重大前景.
- 仔细选择患者对于有效的免疫治疗结果至关重要.
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