单细胞转录组分析揭示了具有侵略性的基底类瘤细胞亚群,与肝内胆管癌的预后不佳有关

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Changyi Liao1, Yuting Zhang2, Jing Yang3

  • 1Cancer Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

Journal of gastroenterology and hepatology
|February 24, 2025
PubMed
概括

研究人员在肝脏内胆固醇癌 (ICC) 中发现了基底类瘤细胞亚群. 这种由HGF-MET信号驱动的侵略性亚型与预后不佳相关,并为ICC提供了新的治疗标.

关键词:
在肝脏内发生的胆固醇癌 (cholangiocarcinoma).一个单细胞RNA测序.瘤异质性的异质性

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