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Updated: Jun 25, 2026

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超低体外体积的微流体白血病化在老鼠模型中是安全有效的

Mubasher Iqbal1, Alexandra L McLennan2,3, Anton Mukhamedshin1

  • 1Department of Biomedical Engineering; University of Houston, Houston, TX, USA.

Nature communications
|February 24, 2025
PubMed
概括

微流体技术为患有超白细胞症的儿童提供了比传统白血更安全的替代方案. 这种新方法有效地去除有害白细胞,同时尽量减少血小板损失等并发症.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...