饮食对抑郁症与肌肉质量和肌肉力量之间的联系的影响:探索相互作用和调解效应
Da Gan1, Xuebiao Wu2, Yingjuan Zhang3,4
1Jiangxi Medicine Academy of Nutrition and Health Management, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, China.
BMC public health
|February 24, 2025
概括
抑郁症与较低的肌肉质量和力量有关. 饮食中的能量摄入量部分解释了这种联系,饮食质量影响了抑郁症患者的肌肉质量.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 精神病学是一个精神病学.
背景情况:
- 抑郁症是一种普遍的疾病,与各种身体健康问题有关.
- 肌肉质量和力量对于保持老年人功能独立至关重要.
- 抑郁症,营养和肌肉健康之间的相互作用需要进一步研究.
研究的目的:
- 为了研究抑郁症,肌肉质量和肌肉力量之间的联系.
- 检查饮食能量摄入量和饮食质量是否改变或调解这些关联.
主要方法:
- 利用了来自2011-2018年国家健康和营养检查调查 (NHANES) 的40岁以上成年人的数据.
- 使用患者健康问卷 (PHQ-9) 评估抑郁症.
- 测量肌肉质量 (SMI) 和力量 (HGS) 并评估饮食摄入量和质量 (HEI-2015).
- 采用多变量线性回归,相互作用和调解分析.
主要成果:
- 抑郁症与较低的骨肌肉指数 (SMI) 和手握强度 (HGS) 有显著的关联.
- 饮食质量 (HEI-2015) 改变了抑郁症和SMI之间的关联.
- 发现饮食能量摄入量调解了抑郁症和SMI和HGS之间的关系.
结论:
- 饮食质量会影响抑郁和肌肉质量之间的关系.
- 减少饮食能量摄入量部分解释了抑郁症与肌肉质量和力量的减少之间的联系.
- 维持充足的饮食能量摄入量和质量对于减轻抑郁症老年人肌肉损失至关重要.
相关概念视频
Depressive Disorders: Etiology
29
Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
29
Depression: Overview
208
Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
208
Exercise and Muscle Performance
1.3K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
1.3K
Human Genetics
520
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
520
Antidepressant Drugs: MAOIs and Other Agents
178
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
178
Stress and Mental Health
71
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
71


