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对仿真抗原受体 (CAR) -T细胞疗法的抗原依赖性耐药性的机制

Fatemeh Nasiri1,2, Pouya Safarzadeh Kozani3,4, Faeze Salem5

  • 1Department of Internal Medicine, College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada.

Cancer cell international
|February 24, 2025
PubMed
概括

当瘤改变标抗原时,CAR-T细胞疗法面临抵抗. 本综述探讨了抗原依赖性耐药机制,并讨论了替代抗原以提高疗效和减少副作用.

关键词:
抗原降低调节的降低调节抗原的损失是对抗原的损失.化学抗原受体的化学抗原受体电阻 电阻 电阻 电阻 电阻 电阻固体瘤是一种固体瘤.有毒性 有毒性

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