长期COVID对心率变化的影响:一个横截面研究
Minyu Qin1, Kwan Lee1, Seok-Ju Yoo2
1Department of Preventive Medicine, College of Medicine, Dongguk University, Gyeongju, Republic of Korea.
BMC infectious diseases
|February 24, 2025
概括
长期的COVID可能会导致年轻人的自主神经系统功能障碍. 长期COVID (LC) 患者,特别是25岁以下患者的自主神经活性异常,显示心率变化 (HRV) 降低.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 长期COVID (LC) 可以表现为症状持续超过一个月的感染后.
- 自主神经系统 (ANS) 可能会受到影响的个体经历LC.
- 在LC阶段,通过心率变化 (HRV) 评估ANS功能至关重要.
研究的目的:
- 在长期COVID (LC) 阶段评估自主神经系统 (ANS) 在轻度至中度COVID-19患者的状态.
- 为了研究LC和心率变化 (HRV) 之间的关系,以衡量ANS功能.
主要方法:
- 一项涉及173名参与者 (COVID-19阳性和阴性) 的横截面研究.
- 参与者根据自我报告的症状被分为LC或没有LC的组.
- 用5分钟的心电图记录和数据分析来测量自主神经系统 (ANS) 功能.
主要成果:
- 在研究组中观察到显著的年龄差异 (p=0.034).
- 较年轻的LC患者 (<25岁) 在非常低频域 (VLF) 中表现出明显较低的心率变化 (HRV) (p=0.012).
- 与非LC组相比,在LC组中发现了异常自主神经活性的更高流行率 (p=0.048).
结论:
- 轻度至中度的COVID-19患者,特别是年轻到中年成人,可能在感染后一个月发展自主功能障碍.
- 长期的COVID与自主神经系统功能的改变有关,由减少HRV和异常神经活性证明.
- 对于经历持续症状的COVID-19幸存者,建议对ANS功能进行早期评估.
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